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Output details

12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering

Imperial College London

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Article title

Characterisation of a soft elastomer poly(glycerol sebacate) designed to match the mechanical properties of myocardial tissue.

Type
D - Journal article
Title of journal
Biomaterials
Article number
-
Volume number
29
Issue number
1
First page of article
47
ISSN of journal
0142-9612
Year of publication
2008
URL
-
Number of additional authors
7
Additional information

Patients at risk of heart failure are often treated using scarce donor transplants. An exploratory approach instead “repairs” the weak section of the heart with a mechanically reinforcing patch that delivers regenerative cells. This paper demonstrates that tailored processing of a particular polymer (PGS) provides a promising solution for “repairing” hearts at risk of failure. This paper was part of the body of work that led to Imperial College €0.388M share of €6.31M for project on elastomeric polymers for cardiac tissue engineering (EU FP-7 214539; 15 partners from 8 EU countries).

Interdisciplinary
Yes
Cross-referral requested
-
Research group
D - Mechanical Engineering
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-