Output details
26 - Sport and Exercise Sciences, Leisure and Tourism
University of South Wales
Transcerebral Exchange Kinetics of Nitrite and Calcitonin Gene-Related Peptide in Acute Mountain Sickness: Evidence Against Trigeminovascular Activation?
International collaboration led by Bailey, funded by The Danish National Research Council including funding for Dr KA Evans as a post-doctoral researcher. First ever human study to demonstrate that the human brain loses nitric oxide during hypoxia (including first rate of exchange calculation) and despite widespread speculation, it does not release the headache molecule, calcitonin gene-related peptide (CGRP), thereby excluding its role in the pathophysiology of acute mountain sickness arguing against the clinical use of CGRP receptor antagonism.