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13 - Electrical and Electronic Engineering, Metallurgy and Materials

University of Surrey

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Article title

Nanocomposite hydroxyapatite formation on a Ti-13 Nb-13Zr alloy exposed in a MEM cell culture medium and the effect of H2O2 addition

Type

D - Journal article

DOI

10.1016/j.actbio.2008.08.008

Title of journal

Acta Biomaterialia

Article number

Volume number

Issue number

First page of article

ISSN of journal

17427061

Year of publication

2009

URL

Number of additional authors

Additional information

Ti-13Nb-13Zr is a new biomedical alloy, replacing Ti-6Al-4V, as it offers excellent corrosion properties, improved biocompatibility and an elastic modulus similar to bone. This paper is having a strong impact (18 citations) as it provides the first detailed characterisation of the native oxide formed on Ti-13Nb-13Zr and a facile methodology for improving the nucleation of hydroxyapatite onto the Ti-13Nb-13Zr surface through immersion in a solution of minimal essential medium (MEM) + H2O2. This surface treatment gives rise to a nanocomposite structure comprised of hydrated TiO2 with island-like regions of hydroxyapatite and amino acids which will strongly promote osseointegration.

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract