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On the process capability of the solid free-form fabrication: a case study of scaffold moulds for tissue engineering.

Tissue regeneration relies on defined scaffolds that facilitate cellular infiltration, nutrient and waste product transport. This paper applies a process capability study to investigate a solid free-form fabrication technique as a manufacturing method to produce scaffolds made from collagen for tissue engineering which create features that ranged up to 1000um. This study demonstrates that, by lowering the temperature of the cooling conditions, the capability of the printing process can be improved (about threefold) to ensure the consistent production of scaffold moulds with dimension characteristics within their specification limits. This study produces a consistent methodology for the production of tissue-engineered scaffolds.