Output details
12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering
University of Birmingham : B - Chemical Engineering
Exploitation of GFP fusion proteins and stress avoidance as a generic strategy for the production of high-quality recombinant proteins
This study, funded by a BBSRC/EPSRC BRIC grant (BB/E005934/1) and in collaboration with Jeff Cole (Biosciences at Birmingham) and GlaxoSmithKline (contact: Dr Richard Hall – co-author) codeveloped novel methods for optimising the production of recombinant proteins in bacterial hosts, an essential step in biopharmaceutical drug development and manufacture. This allows shortening of drug discovery and production development times and synthesis of proteins that were previously difficult to manufacture. The work has been advanced by a BBSRC-funded PhD student and has led to a successful TSB / BBSRC-funded KTP grant with Cobra Biologics (contact: Tony Hitchcock)
