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Output details

15 - General Engineering

Imperial College London

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Output 27 of 109 in the submission

Article title

Determinants of valve gating in collecting lymphatic vessels from rat mesentery.

Type

D - Journal article

DOI

10.1152/ajpheart.00133.2011

Title of journal

American Journal of Physiology-Heart and Circulatory Physiology

Article number

Volume number

301

Issue number

First page of article

H48

ISSN of journal

1522-1539

Year of publication

2011

URL

Number of additional authors

Additional information

The first quantification of lymphatic valve opening/closing behaviour under varying transmural pressures. Cited by groups in UK, Canada, USA and Switzerland in engineering, physiology and clinical journals. Collaboration with physiology groups at Texas A&M and Missouri. Funding: $2.7m NIH grant (R01 HL094269). Inspired adaptation of our previous modelling techniques to account for complex valve behaviour (described in two additional papers). In Physiology Reviews, Wiig and Swartz (Macarthur “Genius Grant” Awardee) said of it, “valves elegantly visualised in rat mesentery in a recent paper”. Resulted in three additional publications, five invited talks (including Columbia and Oxford Universities) and two IP disclosures.

Interdisciplinary

Yes

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract