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12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering

University College London

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Article title

On the fluid dynamics of shaken bioreactors-flow characterization and transition

Type

D - Journal article

DOI

10.1002/aic.13943

Title of journal

AIChE Journal

Article number

Volume number

Issue number

First page of article

334

ISSN of journal

0001-1541

Year of publication

2013

URL

Number of additional authors

Additional information

This paper reports a novel experimental study on the flow dynamics in an orbitally shaken cylinder and offers improved methodologies for scaling of shaken bio-reactors. The research was funded by the EPSRC Advanced research fellowship (Ducci, EP/E055958/1), with technical support from industrial partners Syngenta (Hall, alan.hall@syngenta.com) and BHR group (Ozcan, GOzcan@bhrgroup.co.uk). The laminar to turbulent flow transition and flow scaling law identified in this work have already been successfully applied to assess the mixing time in shaken bio-reactors (ChERD, DOI: 10.1016/j.cherd.2013.1003.1005). The outcomes of this research have strengthened the collaboration with our industrial partner Kühner AG (T. Anderlei, tanderlei@kuhner.com).

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract