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15 - General Engineering

Brunel University London

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Article title

Investigation of Electrostatic Properties of Pharmaceutical Powders Using Phase Doppler Anemometry

Type

D - Journal article

DOI

10.1109/TIA.2010.2045332

Title of journal

IEEE Transactions on Industry Applications

Article number

Volume number

Issue number

First page of article

1181

ISSN of journal

0093-9994

Year of publication

2010

URL

http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=5438803

Number of additional authors

Additional information

Electrostatic charge generated during pharmaceutical drug dispensing using DPIs causes fluctuation in the dose released due to triboelectrification within the device. Pharmaceutical industry needed an instrument capable of monitoring the bipolar charge of the drug aerosol released from such devices to understand the charging mechanisms and then to develop devices in which the charging process can be controlled. In a previous research (funded by GSK), PDA based bipolar charge measurement system was developed to monitor aerosols delivered by pMDIs. This system (funded by Pfizer) was further developed for aerosols delivered by DPIs as the powder morphologies are more complex.

Interdisciplinary

Cross-referral requested

Research group

1 - Sensors and Systems

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract