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15 - General Engineering

University of Oxford

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Output 30 of 354 in the submission

Article title

Adaptive optics enables 3D STED microscopy in aberrating specimens

Type

D - Journal article

DOI

10.1364/OE.20.020998

Title of journal

OPTICS EXPRESS

Article number

Volume number

Issue number

First page of article

20998

ISSN of journal

1094-4087

Year of publication

2012

URL

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=000308865600043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=4fd6f7d59a501f9b8bac2be37914c43e

Number of additional authors

Additional information

The STED method is revolutionizing optical microscopy by providing resolutions in the 10s of nanometers range, far smaller than the physical diffraction limit of light. However, full 3D resolution is very difficult to obtain, due to optical aberrations from specimens. This paper showed the first demonstration of specimen aberration correction, enabling 3D STED imaging deep in biological tissue. These results have already led to over ten invitations to speak at conferences, including a plenary talk at Focus on Microscopy 2013.

Interdisciplinary

Cross-referral requested

Research group

C - Electrical and Electronic Engineering

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract