Output details
3 - Allied Health Professions, Dentistry, Nursing and Pharmacy
Edinburgh Napier University
Article title
A Central Role for CK1 in Catalyzing Phosphorylation of the p53 Transactivation Domain at Serine 20 after HHV-6B Viral Infection
Type
D - Journal article
Title of journal
Journal of Biological Chemistry
Article number
-
Volume number
283
Issue number
42
First page of article
28563
ISSN of journal
1083-351X
Year of publication
2008
URL
-
Number of additional authors
8
Additional information
My role in the paper was to express and purify the full length tetrameric p53 protein from e.coli. This reagent was used throughout the paper in the analytical assays and was essential for the analysis of the various fractions from infected cells and in detecting kinase activity (figures 1 – 3, 7 – 8 and 10). I also gave advice and practical assistance to the student (Bodil Oster) as to how to carry out the in vitro kinase and phosphorylation assays with the p53 protein.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Citation count
14
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
