Output details

Optimised production of multifunctional microfibres by microfluidic chip technology for tissue engineering applications

Significance of output:

Each year, millions of patients suffer from organ damage or failure where insufficient number of donors are available for transplantation. Tissue engineering to construct artificial tissues/organs has emerged to address this need where suitable scaffolds are essential to direct the construction with desired shape and mechanical properties. We developed a microscale fluidic system to fabricate microfibles with biocompatible polymers to function as tissue engineering scaffolds. The method has significant controllability for microfibles’ shape and properties with multifunction of encapsulating different cells and drugs which is not achievable in conventional methods. This resulted from an international and multidisciplinary collaboration.