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Output details

11 - Computer Science and Informatics

University of Oxford

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Article title

Programmable chemical controllers made from DNA

Type
D - Journal article
Title of journal
Nature Nanotechnology
Article number
-
Volume number
8
Issue number
10
First page of article
755
ISSN of journal
1748-3387
Year of publication
2013
URL
-
Number of additional authors
6
Additional information

<27>

This paper reports on experimental results about a new DNA computational architecture, previously presented by myself in a theory paper. It demonstrates an entirely new manufacturing technology for DNA computing, based on bacterially-produced plasmidic DNA, which bypasses inherent quality and length limitations of synthetic DNA. We demonstrate that this architecture can quantitatively emulate Chemical Reaction Networks, and we are therefore able to engineer any system that can be expressed as a finite set of chemical reactions with prescribed rates. That is, we can for the first time use chemistry as an executable programming language, as opposed to a modeling language.

Interdisciplinary
-
Cross-referral requested
-
Research group
None
Citation count
1
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-