Impact (REF3a/b)

Impact template (REF3a)

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All impact case studies

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Individual case studies

Case Study 1. The Acute Infarct Ramipril Efficacy Study: a simple treatment to improve survival after acute myocardial infarction (50K)

Case Study 10. Improving lives and transforming services for Paroxysmal Nocturnal Haemoglobinuria (PNH), a life-threatening, disabling blood disorder (51K)

Case Study 2: Clinical trials show that the novel cytotoxic drug eribulin prolongs survival in women with heavily pre-treated metastatic breast cancer (50K)

Case Study 3. Establishing the effectiveness of laparoscopic surgery for colorectal cancer leading to safer implementation into the NHS and world-wide for greater a patient benefit (50K)

Case Study 4. Improving chemotherapy, radiotherapy and patient outcomes for colorectal cancer through patient-focused integrated clinical trials (73K)

Case Study 5. Pathology research led to an international reduction in rectal cancer recurrence and death by improving multidisciplinary clinical practice (49K)

Case Study 6: Transforming the treatment of myeloma has produced significant improvement in patient survival: the MRC Myeloma trials (50K)

Case Study 7. Changing the treatment paradigm of rheumatoid arthritis: early diagnosis and aggressive treatment to attain remission leads to sustained improvements in health and quality of life (48K)

Case Study 8. Transforming the diagnosis and clinical management of autosomal recessive disease. (65K)

Case Study 9. Changing cancer services and improving patient outcomes in the UK (143K)