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Output details

11 - Computer Science and Informatics

University of Edinburgh

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Output 328 of 401 in the submission

Article title

Standard Anatomical and Visual Space for the Mouse Retina: Computational Reconstruction and Transformation of Flattened Retinae with the Retistruct Package

Type

D - Journal article

DOI

10.1371/journal.pcbi.1002921

Title of journal

PLoS Computational Biology

Article number

e1002921

Volume number

Issue number

First page of article

ISSN of journal

1553-734X

Year of publication

2013

URL

http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1002921

Number of additional authors

Additional information

<28> Originality: A new method for the open problem of reconstructing a cut and flattened 2D manifold embedded in 3D space back into its original shape. It is applied to the particular case of reconstructing an image of a flattened retina provided from experiment.

Significance: A novel computational approach applied to a basic neurobiological problem. The ability to reliably map a host of retinal structural features into visual space for central nervous system topological analysis, physiological assessment, behavioural correlations and developmental analysis are examples of the many possible applications.

Rigour: Method validated on 297 samples. Software available as open source.

Interdisciplinary

Cross-referral requested

Research group

B - Institute for Adaptive & Neural Computation

Citation count

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract