Output details
15 - General Engineering
King's College London
Article title
Colorectal Tumor Vascularity: Quantitative Assessment with Multidetector CT—Do Tumor Perfusion Measurements Reflect Angiogenesis?
Type
D - Journal article
Title of journal
Radiology
Article number
-
Volume number
249
Issue number
2
First page of article
510
ISSN of journal
0033-8419
Year of publication
2008
URL
-
Number of additional authors
5
Additional information
This highly cited paper (88 citations, Oct 13) was the first to demonstrate a correlation between Perfusion CT and angiogenesis as determined by histopathology. Angiogenesis is a key biological signature in cancer and this study led to Perfusion CT being established as an important biomarker for cancer imaging (>65 cancer related papers in 2012). Perfusion CT is now used to assess vascular response to locoregional therapies and in Phase I/II trials of novel drugs. This paper is published in the leading journal in imaging.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
