Output details
11 - Computer Science and Informatics
Brunel University London
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Article title
Cell fate decisions are specified by the dynamic ERK interactome
Type
D - Journal article
DOI
Title of journal
Nature Cell Biology
Article number
-
Volume number
11
Issue number
12
First page of article
1458
ISSN of journal
1476-4679
Year of publication
2009
Number of additional authors
11
Additional information
<28> Published in a leading journal whose 5-year Impact Factor is 20.691 according to ISI Web of Knowledge, the paper is concerned with the construction and validation of a very rigorous and formal computational model of a highly important core biochemical pathway. It has made a major contribution to the understanding of the cell-fate mechanism, and is the first to show that this is based on an integrative rather than a binary switch mechanism.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Citation count
86
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-