Staff members (REF1a/c)

• None

• None

• None

• None

• None

• None

Dr Murray Brunt is a Consultant Clinical Oncologist employed by University Hospital of North Staffordshire NHS Trust (UHNS) since 1991 and clinical lead of UHNS Cancer Clinical Trials Unit since 1996 when he set it up, with 2 clinical research sessions weekly from 2011. In 2007 Dr Brunt joined the Research Institute for Science & Technology in Medicine and in 2012 awarded Honorary Senior Lecturer at Keele University. His major research interest is breast cancer clinical trials, as clinical co-coordinator of £3.6m HTA-funded FAST-Forward, UK Chief Investigator (two international trials), trial management groups of eight other trials and also principal investigator and recruiter to over 60 studies; including research interests in lymphomas and skin cancer. Recent trials include HERA where he was co-author of the practice-changing publication in The Lancet and PRESENT treating the first patient in Europe in the groundbreaking first phase 3 breast cancer vaccine trial.

Dr Brunt’s work involves collaboration with members of Keele and UHNS allied health professions and all clinical trial funds are managed through Keele accounts which has realised over £0.5m. Dr Brunt chairs the Royal College of Radiologists breast group and was chair of the Cancer Network R&D steering committee for 6 years. [200 words

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

Specific Research Responsibilities – Dr Konstantinou was appointed in March 2005 to a clinical academic post of Research Physiotherapist and Clinical Specialist in Spinal Physiotherapy, now jointly held between Keele University and Staffordshire and Stoke-on-Trent NHS Partnership Trust. Her clinical academic appointment includes five academic sessions (exclusively based at Keele) underpinned by a secondment agreement, and joint management and clinical academic appraisal arrangements. She has a formal job plan, setting out her clinical and academic sessional responsibilities, which is annually reviewed at her appraisal. She is a core member of Keele’s Arthritis Research UK Primary Care Centre, responsible for: the “medium risk” intervention which formed part of Keele’s StartBack trial, PI for the ATLAS study (one of three work streams within Keele’s NIHR Programme Grant Optimising management of spinal pain in primary care; 2009 - 2014); Co-applicant on a new Trial for Stratified Care of Sciatic pain (short-listed by the HTA). Keele has successfully supported her to gain an NIHR Clinical Lectureship (2010 – 2013) and more recently a HEFCE Senior Clinical Lectureship. Dr Konstantinou’s HECFE award is managed via Keele.

• None

• None

• None

• None

• None

• None

• None

• None

• None

• None

Prof PMS (Shaughn) O’Brien was appointed as the Foundation Clinical Professor of Obstetrics and Gynaecology at Keele University Medical School in 1989 and has maintained a close working relationship between Keele and the University Hospital of North Staffordshire (UHNS) for almost 25 years. At the time of RAE2008 he was on the Keele payroll but is currently an employee of UHNS. Prof O’Brien has been active in research throughout this time, having an average of two half-day sessions per week for research and has maintained an active Keele laboratory and staff team. His obstetrics research areas include pre-eclampsia, fetal monitoring by computerised ECG and Near Infra-Red Spectroscopy, labour ward management including instrumental delivery and perineal trauma;. His gynaecological research includes medical and diagnostic gynaecology, disorders of the menstrual cycle and premenstrual syndrome. Research grant support has included industrial, NIHR, charitable and European Commission funds, all managed through Keele University accounts. He has produced over 300 publications including peer-reviewed articles, book chapters and text books. Prof O’Brien has served in the Royal College of O&G through many roles including as Vice President responsible for national standards, including patient safety, professional standards, clinical standards and the broad area of the NHS reforms.

• None

• None

• None

• None

• None

• None

• None

Christine Roffe is employed by North Staffordshire Combined Health NHS Trust as lead of the West Midlands Stroke Research Network and holds an honorary contract as consultant stroke physician at the University Hospital of North Staffordshire, where she leads one of only eight NIHR funded hyperacute stroke research units in England. She joined Keele University as a honorary Senior Lecturer in October 1996, becoming a Keele Professor in 2010. She has developed a strong multidisciplinary stroke research group, linking to a number of Keele research groups including rehabilitation, psychology, social gerontology, imaging, pharmacy, bioengineering & therapeutics. Her research interests are interventions for acute stroke and stroke rehabilitation. Roffe is the chief investigator of the Stroke Oxygen Study (www.so2s.co.uk/), a large multicentre RCT of oxygen supplementation after acute stroke with over 8,000 patients recruited from 130 centres, funded by the NIHR Health Technology Assessment Programme at £1.4m. Other studies include a RCT of metoclopramide in the prevention of pneumonia after stroke, experimental studies comparing different thrombectomy devices, studies of Botulinum toxin and electrical stimulation early after stroke, and novel imaging technologies for stroke diagnosis. All these projects are collaborative with Keele-employed academic staff, all funds are managed through the University’s accounts.

• None

• None

• None

• None

• None

• None

• None