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Output details

13 - Electrical and Electronic Engineering, Metallurgy and Materials

University of Sheffield : B - Materials Science and Engineering

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Output 30 of 128 in the submission

Article title

Development of biodegradable electrospun scaffolds for dermal replacement

Type

D - Journal article

DOI

10.1016/j.biomaterials.2008.03.037

Title of journal

Biomaterials

Article number

Volume number

Issue number

First page of article

3091

ISSN of journal

01429612

Year of publication

2008

URL

http://www.ncbi.nlm.nih.gov/pubmed/18448164

Number of additional authors

Additional information

This paper is one of the first studies to take electrospun biodegradable scaffolds into animal experiments to assess the biocompatibility and immune response to the scaffolds. It shows how these scaffolds can be made to breakdown predictably and gives a solid foundation for how to use these for tissue engineering. The specific application in this paper was for the development of a biodegradable synthetic scaffold to replace the use of human donor dermis in tissue engineering. This has now attracted NHS Burns Service Development funding (£58k in 2014) to develop this for skin reconstruction for clinical use.

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract