Output details
15 - General Engineering
King's College London
Article title
Assessment of Response to Tyrosine Kinase Inhibitors in Metastatic Renal Cell Cancer : CT Texture as a Predictive Biomarker
Type
D - Journal article
Title of journal
Radiology
Article number
-
Volume number
261
Issue number
1
First page of article
165
ISSN of journal
0033-8419
Year of publication
2011
URL
-
Number of additional authors
5
Additional information
This study investigating the feasibility of heterogeneity analysis as a novel responsive and predictive biomarker was the first to demonstrate that CT texture changes may be associated with clinical outcome (progression free survival) in metastatic renal cancer. Assessment of image texture in addition to size and enhancement may improve patient response categorisation in the clinic. Its generalisibility is being studied in a large multicentre NIHR funded clinical trial (STAR), to provide additional supportive evidence for clinical translation.This paper is published in the leading journal in imaging.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
