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In situ wavefront correction and its application to micromanipulation

Optical aberrations - distortions to a propagating wavefront are severely detrimental to performance in imaging, nanosurgery and micromanipulation, as well as other techniques within modern microscopy. The paper presents a generic method allowing compensation of all aberrations along the entire optical train. The power of the method was demonstrated for the field of micromanipulation, which is very sensitive to wavefront distortions. We showed direct trapping with optimally focused laser field carrying power of a fraction of a milliwatt as well as the first trapping through highly turbid and diffusive media. By now, the method was adopted by number of researchers.