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15 - General Engineering

University of Northumbria at Newcastle

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Article title

A systems engineering approach to validation of a pulmonary physiology simulator for clinical applications

Type

D - Journal article

DOI

10.1098/rsif.2010.0224

Title of journal

Journal of The Royal Society Interface

Article number

Volume number

Issue number

First page of article

ISSN of journal

1742-5662

Year of publication

2010

URL

Number of additional authors

Additional information

This article describes a systems engineering framework for the validation of an in silico simulation model of pulmonary physiology, which can be employed for parameter settings optimization to minimize potential risks of the patients’ lungs from mechanical ventilation and maximize oxygenation efficiency leading to clinical advices. The work is one outcome of the EPSRC projects (EP/F057016/1, £200k; EP/F057016/2, £100k) in collaboration with Queens Medical Centre at Nottingham. This work has led to further grants (EPSRC: EP/1036680/1, £451k; MRC: G1002017, £172k) and an invited talk at TED Exeter (Technology, Entertainment, Design) in April 2013.

Interdisciplinary

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract