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Quantitative characterization of turbid media using pressure contrast acousto-optic imaging

Acousto-optic (AO) sensing, pioneered by Prof. Roy’s group, employs the nonlinear interaction of light and sound to sense optical contrast in diffusive media. Normally used to image absorption, this paper demonstrates, for the first time, the ability of AO to quantitatively sense and image contrast in scattering. The technique shows promise for imaging and characterizing tissues located relatively deep in optically accessible organs. This is one of a series of papers through which Roy’s group has built a bridge between the biomedical optics and ultrasonics communities. Their AO work is the basis for one pending US patent application.