Impact (REF3a/b)

Impact template (REF3a)

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All impact case studies

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Individual case studies

Better diagnosis and treatment for patients with myeloproliferative neoplasms (50K)

Better treatment of anaemia and improved quality of life in patients with chronic kidney disease (31K)

Early pulmonary rehabilitation reduces re-admissions and improves survival of patients admitted to hospital with acute flare-ups of chronic obstructive pulmonary disease (COPD) (165K)

Fewer deliveries by caesarean section in HIV-infected women and less mother-to child transmission due to improved antiretroviral treatment during pregnancy (191K)

Improved methods for preimplantation genetic diagnosis help couples avoid the risk of bearing children with inherited diseases (188K)

Improved patient recovery and reduced mortality through the use of non-invasive ventilation (NIV) during acute exacerbations of chronic obstructive pulmonary disease (COPD) (169K)

Improved survival of patients with acute promyelocytic leukaemia due to personalised treatment and early warning of re-occurrence (193K)

Improved treatment and quality of life for patients with overactive bladder syndrome through developing new ways of administering Botulinum Toxin–A (35K)

Improved understanding of the risk of cardiovascular disease with hormone therapy for prostate cancer (112K)

Slowing the progression of diabetic kidney disease (131K)

Studies on childhood peanut allergy reverse the guidelines to avoid peanuts in infancy (221K)

Successful and cost-effective methods of controlling the spread of MRSA (methicillin-resistant Staphylococcus aureus) in hospitals (192K)

The development of “personalised treatments” for BRCA1 and BRCA2 associated breast and ovarian cancers using PARP inhibitors to prolong life (145K)

Uncovering new titin mutations to develop better clinical tests and treatments that improve outcomes in patients with genetic muscle disease (128K)

Using intensive conventional drug treatment to optimise clinical outcomes in rheumatoid arthritis (141K)