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Membrane enhanced peptide synthesis.

This paper reports Membrane Enhanced Peptide Synthesis (MEPS), a technology platform invented and developed at Imperial and covered by international patent applications (PCT/GB2009/050,990; PCT/GB2009/051,525). Both patent applications have been licensed by Evonik Membrane Extraction Technology Ltd (yuri.bouwhuis@evonik.com). The MEPS process advantageously combines organic solvent membrane separation with peptide synthesis, and can be extended to further synthetic processes such as oligonucleotide synthesis, the subject of an on-going collaboration with GSK (£190K to date) in oligonucleotide process technology (Mark Buswell, andrew.m.buswell@gsk.com). MEPS has recently been highlighted for its potential as a new manufacturing technology in Speciality Chemicals Magazine, May 2013 (www.cpcscientific.com/pdfs/spe-chemicals-magazine-article.pdf).