Output details
11 - Computer Science and Informatics
Manchester Metropolitan University
Article title
A reconfigurable NAND/NOR genetic logic gate
Type
D - Journal article
Title of journal
BMC Systems Biology
Article number
-
Volume number
6
Issue number
1
First page of article
126
ISSN of journal
1752-0509
Year of publication
2012
URL
-
Number of additional authors
1
Additional information
<2>Output of the EU FP7 BACTOCOM project (FP7-ICT-2009-4 248919, coordinated by MMU). Listed by the journal as a “Highly Accessed” paper. First known description of a genetic logic device that can be dynamically switched between functional modes (NAND/NOR) without modification. The significance of our model lies in its inherent noise resistance, which is a major issue in synthetic biology. We present extensive simulation results, including realistic consideration of spatial and physical force factors, which yield important insights into population-level behaviour of engineered cells.
Interdisciplinary
Yes
Cross-referral requested
-
Research group
A - Biological and Sensory Computation
Citation count
2
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
