You are in : Home » Results & submissions » Select UOA » 13 - Electrical and Electronic Engineering, Metallurgy and Materials » View submission: University of Ulster » Outputs » Detail

Output details

13 - Electrical and Electronic Engineering, Metallurgy and Materials

University of Ulster

Return to search Previous output Next output

Output 11 of 71 in the submission

Article title

Assessment of an osteoblast-like cell line as a model for human primary osteoblasts using Raman spectroscopy

Type

D - Journal article

DOI

10.1039/C2AN16209A

Title of journal

Analyst

Article number

Volume number

137

Issue number

First page of article

1559

ISSN of journal

0003-2654

Year of publication

2012

URL

http://pubs.rsc.org/en/Content/ArticleLanding/2012/AN/c2an16209a

Number of additional authors

Additional information

The use of osteosarcoma derived osteoblast-like cell lines as an alternative to human primary cells is controversial. We provide definitive evidence that the standard U20S osteosarcoma cell is not a good model for human osteoblasts and instead they may serve as a model for composition differences between normal bone and osteoblastic lesions. This work derived from the REMEDI project on regenerative medicine (EP/C534247/1), involved collaboration with Dublin Institute of Technology and resulted in an invited paper at UKSAF 2012 (uksaf.org).

Interdisciplinary

Cross-referral requested

Research group

A - Biomaterials

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract