Output details
15 - General Engineering
University of Southampton
Evaluation of a new high power, wide separation laser Doppler probe: potential measurement of deeper tissue blood flow
Significance of output:
There is an unmet need to make simple non-invasive measurements of biomarkers in tissues key to the pathogenesis of cardiovascular disease, e.g. muscle and adipose tissue. Laser Doppler fluximetry (LDF) had previously only been used to examine blood flow and response to stimuli in superficial (dermal) tissue. Theoretical, simulation and human studies are used to assess the capabilities of a high power device capable of measuring larger tissue volumes in-vivo in deeper tissue than before. Techniques for wavelet analysis of LDF signals developed in this study are now provided with software distributed by the manufacturer (contact gush@moor.co.uk, http://gb.moor.co.uk/product/moorvms-ldf1-hp-high-power-ldf/5).