Output details

Flexible acoustic particle manipulation device with integrated optical waveguide for enhanced microbead assays

Significance of output:

- By combining accurate acoustic particle positioning and optical evanescent detection we demonstrate a new class of sensor. Unusually, the design allows multiple types of acoustic mode, permitting particles such as functionalised beads, cells or bacteria to be both attracted and repelled from active surfaces. The paper has led to design consultancy with ‘Prokyma Ltd.’, who have developed a diagnostic device for TB detection in the field. They use our acoustic technology to aggregate and wash functionalised capture beads. The technology also has potential application in water quality monitoring, and the detection of parasites, circulating tumour cells and other pathogens.