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13 - Electrical and Electronic Engineering, Metallurgy and Materials

University of Bath

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Article title

Label-free detection of protein interactions with peptide aptamers by open circuit potential measurement

Type

D - Journal article

DOI

10.1016/j.electacta.2008.04.036

Title of journal

Electrochimica Acta

Article number

Volume number

Issue number

First page of article

6489

ISSN of journal

0013-4686

Year of publication

2008

URL

http://dx.doi.org/10.1016/j.electacta.2008.04.036

Number of additional authors

Additional information

This paper demonstrates for the first time that electrical detection of protein interactions can be achieved by direct measurement of open-circuit potential variations. This interdisciplinary study led by Estrela involves collaborations with leading groups in the clinical and life sciences. The results enable the construction of portable and inexpensive biosensors for the label-free detection of protein interactions in a wide range of applications, including medical diagnostics.

Interdisciplinary

Yes

Cross-referral requested

Research group

A - Advanced Sensor Technologies

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract