Output details
15 - General Engineering
University College London
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Output 0 of 0 in the submission
Article title
The development of fibronectin-functionalised hydroxyapatite coatings to improve dermal fibroblast attachment in vitro.
Type
D - Journal article
Title of journal
J Bone Joint Surg Br
Article number
-
Volume number
94
Issue number
4
First page of article
564
ISSN of journal
0301-620X
Year of publication
2012
Number of additional authors
2
Additional information
This was the first manuscript to demonstrate that fibronectin (an extracellular matrix protein) functionalized hydroxyapatite will significantly increase dermal fibroblast attachment in vitro. It is critical that fibroblasts in the dermis, attach to biomaterials that are used for skin-penetrating implants to support the overlying epithelium and prevent downgrowth and infection. In addition, it provided a foundation for further in vivo research. These coatings could be used to create custom adhesive implant surfaces for transcutaneous amputation prostheses.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
