Output details
15 - General Engineering
University College London
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Article title
Targeted magnetic delivery and tracking of cells using a magnetic resonance imaging system.
Type
D - Journal article
Title of journal
Biomaterials
Article number
-
Volume number
31
Issue number
20
First page of article
5366
ISSN of journal
1878-5905
Year of publication
2010
URL
-
Number of additional authors
5
Additional information
This paper described a new approach of mine to the targeted delivery of magnetically-labelled cells using the gradient coils in an MRI scanner. It drew on my experience and understanding of the actuation of cells in inhomogeneous fields, and took the unprecedented step of over-driving the gradient coils to create usable forces on the cells. The paper established the principle of action in vitro. Subsequent work has been on a rabbit model of human vascular disease (diabetic foot). This work formed the basis of a £250k EPSRC follow-on project, now under way, and was patented in 2010.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-