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The physiological origin of task-evoked systemic artefacts in functional near infrared spectroscopy.

This paper and work is part of a collaboration that I have established between the Physikalisch-Technische Bundesanstalt (PTB) in Berlin, GERMANY; and Freie Universität in Berlin, GERMANY with my group in UCL. The paper uses a novel approach by combining two state-of-the-art technologies to image brain function and investigates the effect of systemic physiology (such as blood pressure) in monitoring the functional brain. This paper in particular challenges the functional localisation results from non-invasive functional near-infrared spectroscopy methodology suggesting that interference from extracranial vasculature can produce erroneous results. We prove this hypothesis by using functional magnetic resonance imaging and angiography.