Output details
13 - Electrical and Electronic Engineering, Metallurgy and Materials
University of Ulster
Article title
Glutathione-mediated release of Bodipy from PEG cofunctionalized gold nanoparticles
Type
D - Journal article
Title of journal
International Journal of Nanomedicine
Article number
-
Volume number
7
Issue number
-
First page of article
4007
ISSN of journal
1178-2013
Year of publication
2012
URL
-
Number of additional authors
2
Additional information
Following on from our earlier work on PEG coating of nanoparticles, this paper reports on its effect on payload release under intracellular conditions. We discovered that PEG inhibits the initial burst release of payload and nanoparticle aggregation and that reduced PEG is effective thus enabling the co-attachment of large amounts of drug payload. This work has led to a collaboration with Queens University Departments of Physics and Pharmacy and a funding proposal to Prostate Cancer UK which is currently under review.
Interdisciplinary
-
Cross-referral requested
-
Research group
A - Biomaterials
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
