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Output details

12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering

University of Birmingham : B - Chemical Engineering

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Article title

Exposure of Salmonella enterica Serovar Typhimurium to High Level Biocide Challenge Can Select Multidrug Resistant Mutants in a Single Step

Type
D - Journal article
Title of journal
PLoS ONE
Article number
-
Volume number
6
Issue number
7
First page of article
e22833
ISSN of journal
1932-6203
Year of publication
2011
URL
-
Number of additional authors
3
Additional information

This study was the first to investigate the effects of biocides on bacteria using flow cytometry. This allowed not only detection of viable cells upon exposure to biocides that were undetectable by other methods, but also characterisation of resistant mutants which have previously been impossible to isolate. This enables future research into safe biocide use, critical for human and veterinary health. Work was in collaboration with Dr Mark Webber from Infection & Immunity at Birmingham, and used BBSRC-funded equipment (BB/F011237/1, TWO CoI). This has strengthened links with the Webber/Piddock research group, which continue in the form of collaborative research.

Interdisciplinary
-
Cross-referral requested
-
Research group
B - Bioengineering
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-