Output details
3 - Allied Health Professions, Dentistry, Nursing and Pharmacy
University of Northampton
Matrix metalloproteinase genes on chromosome 11q22 and the risk of anterior cruciate ligament (ACL) rupture.
The international authors combine geneticists, cell biologists, Orthopaedic Surgeons and a Sports Physician to produce a basic science project with major clinical implications. The findings have formed the basis for a programme of work which includes a patent and its commercial development.
I decided that both the MMP3 and the MMP10 SNPs should be investigated, and that taqman technology should be used for this study. I received funding for a postdoc from the Leverhulme Trust. I trained the postdoc, suggested the DNA sample plate design for genotyping, assisted with preliminary data analysis, interpreting the findings and drafting the manuscript.
