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Output details

15 - General Engineering

London South Bank University

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Article title

A Process Analytical Technology Based Investigation of the Polymorphic Transformations during the Antisolvent Crystallization of Sodium Benzoate from IPA/Water Mixture

Type
D - Journal article
Title of journal
Crystal Growth & Design
Article number
-
Volume number
9
Issue number
9
First page of article
3964
ISSN of journal
1528-7505
Year of publication
2009
URL
-
Number of additional authors
5
Additional information

This research is the outcome of a successful collaboration with a major global, biopharmaceutical company, AstraZeneca (EPSRC CASE award supported by AstraZeneca). This study confirmed the formation of a new, previously unreported channel solvate, which transforms into a channel hydrate during antisolvent crystallisation experiments. This work has already created significant industrial interest and the results have drawn the attention of Pharmaceutical and Analytical R&D work at AstraZeneca. Verification: Dr Amy Robertson, AstraZeneca, E-mail: amy.robertson@astrazeneca.com

Interdisciplinary
-
Cross-referral requested
-
Research group
2 - Chemical and Process Engineering
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-