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Output details

15 - General Engineering

Queen Mary University of London

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Output 51 of 81 in the submission
Article title

Osteoinductive ceramics as a synthetic alternative to autologous bone grafting.

Type
D - Journal article
Title of journal
Proc Natl Acad Sci U S A
Article number
-
Volume number
107
Issue number
31
First page of article
13614
ISSN of journal
1091-6490
Year of publication
2010
URL
-
Number of additional authors
8
Additional information

This paper reports the development of an entirely new class of calcium phosphate biomaterials that leads to induction and regeneration of bone. Their bone regeneration potential is similar to that of the clinical gold standard autograft and bone growth factor rhBMP2 (annual sales totalling 1 billion US$) and they are superior over all other synthetic biomaterials. The results have aided in a commercial contract between Progentix and NuVasive totalling US$80 million, 9 invited (keynote) lectures and will lead to altered clinical practise (to date more than 10,000 devices have been implanted in the US, EU, Australia, New Zealand and Brazil).

Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-