Output details
11 - Computer Science and Informatics
Newcastle University
Article title
Neural Development Features: Spatio-Temporal Development of the Caenorhabditis elegans Neuronal Network
Type
D - Journal article
Title of journal
PLoS Computational Biology
Article number
e1001044
Volume number
7
Issue number
1
First page of article
-
ISSN of journal
1553-7358
Year of publication
2011
Number of additional authors
1
Additional information
<28> This manuscript in the leading computational biology journal is the first article describing the formation of a biological neural network and was viewed 4,000 times online. Contrary to the previous paradigm in the field for establishing long-distance connections through guidance cues, such connections are mainly formed when the neurons are nearby. This mechanism might also explain changes in long-distance connectivity for developmental brain disorders. This paper, which led to a press release featured in US News and Bloomberg Business, was crucial in securing EPSRC funding to study human brain development (£465k, EP/K026992/1).
Interdisciplinary
-
Cross-referral requested
-
Research group
A - Biology, Neurosciences and Computing
Citation count
9
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
