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Output details

15 - General Engineering

University of Leicester

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Output 52 of 99 in the submission
Article title

Mechanisms contributing to central excitability changes during hearing loss.

Type
D - Journal article
Title of journal
Proc Natl Acad Sci U S A
Article number
-
Volume number
109
Issue number
21
First page of article
8292
ISSN of journal
1091-6490
Year of publication
2012
Number of additional authors
7
Additional information

This research allowed us to understand the neural mechanisms leading to hearing loss after exposure to loud-noise. The work was the result of an interdepartmental collaboration involving experiments and modelling. The computational model I implemented guided my collaborators into performing experiments that showed why hearing loss can be reversible in certain cases. This work is the basis of a PhD project (funded by the UK charity Action on Hearing Loss), and a grant application to investigate ways of slowing down the myelin degeneration to alleviate effects on hearing loss and tinnitus. The article has also attracted attention from the media.

Interdisciplinary
Yes
Cross-referral requested
-
Research group
A - Bioengineering
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-