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Practical methods for noise removal: applications to spikes, nonstationary quasi-periodic noise, and baseline drift.

This publication describes key data-processing methodologies required to measure the neurochemical effects of spreading depolarisation waves in the human brain. They allowed subsequent detection of glucose and lactate changes in all 90 waves seen in 10 patients (Journal Cerebral Blood Flow and Metabolism 2010;30:1343-1355) and hence use of system in international clinical centres. Led to invitations to be symposium organiser at Pittcon 2010 (Florida), lecturing faculty at Gordon Research Conference on Bioanalytical Sensors, Newport RI (2012) and symposium speaker in 26th International Society of Electrochemistry meeting, Nice (2010). Helped PhD student Feuerstein gain Alexander von Humbolt Fellowship.