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13 - Electrical and Electronic Engineering, Metallurgy and Materials

University of Ulster

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Article title

Influence of surface topography on osteoblast response to fibronectin coated calcium phosphate thin films

Type

D - Journal article

DOI

10.1016/j.colsurfb.2010.03.013

Title of journal

Colloids and Surfaces B: Biointerfaces

Article number

Volume number

Issue number

First page of article

283

ISSN of journal

09277765

Year of publication

2010

URL

Number of additional authors

Additional information

This paper addresses bio-implant surface engineering and the influential role of extracellular matrix proteins, which are critical factors in the development of medical implants. Using surface chemistry and topography to create a specific biomaterial micro-environment, we demonstrate induced proliferation, differentiation and mineralisation of bone cells in vitro, as a key enabling step for tissue engineering scaffold manufacture. Funded under the All-Ireland Functional Biomaterials R&D programme, this work has now attracted Proof of Concept commercialisation finance (InvestNI, PoC 319, 2013).

Interdisciplinary

Cross-referral requested

Research group

A - Biomaterials

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract