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Output details

15 - General Engineering

Imperial College London

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Output 5 of 109 in the submission

Article title

A model of giant vacuole dynamics in human Schlemm's canal endothelial cells.

Type

D - Journal article

DOI

10.1016/j.exer.2010.11.003

Title of journal

Experimental Eye Research

Article number

Volume number

Issue number

First page of article

ISSN of journal

1096-0007

Year of publication

2011

URL

Number of additional authors

Additional information

This paper established the first cell culture model that reproduced key cell biomechanical functions involved in glaucoma pathogenesis. It led to 3 invited talks at international conferences (2012: International Congress of Eye Research, BMES, 2010: ARVO), formed the basis for the 2013 International Research Scholar Award to Overby, led to two invited commentaries published in International Glaucoma Review (2010,2011), and a moderator position for the 2012 ARVO-Pfizer Ophthalmics Research Institute. This model generated preliminary data for our second NIH funded R01 ($400k to Overby as co-PI; EY022359, 2012 ) and a grant from Fight for Sight Research Foundation (£100k; 1385).

Interdisciplinary

Yes

Cross-referral requested

Research group

None

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract