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The use of injectable forms of fibrin and fibronectin to support axonal ingrowth after spinal cord injury

This collaborative study reported that protein material blends of fibrin with fibronectin, purified from human blood, could be fabricated to an injectable, fast-setting material. The composition of this blend and its fibre micro-structure was shown to be an effective substrate stimulating spinal regeneration. Its injectability and gelling within spinal cavities makes it a potential for treatment for late, chronic degeneration following spinal injuries. This study showed that the material is effective in chronic injuries and in future may be used with neural stem cells which would have impact on spinal cord repair in humans.