Output details
15 - General Engineering
University College London
Return to search
Output 0 of 0 in the submission
Article title
The effects of microporosity on osteoinduction of calcium phosphate bone graft substitute biomaterials.
Type
D - Journal article
Title of journal
Acta Biomater
Article number
-
Volume number
8
Issue number
7
First page of article
2788
ISSN of journal
1878-7568
Year of publication
2012
URL
-
Number of additional authors
7
Additional information
The shows for the first time osseoinductivity, thought to be a property associated with cytokines such as bone morphogenic proteins (BMP), can be engineered by changing the morphology of a bone graft substitute materials. These materials are used for spinal fusions with over 200,000 spinal fusion procedures performed in the United States annually, with a success rate of 70%. BMPs have been shown to be problematic in these applications. By using more osseoinductive graft material success rate may be improved. This has led to a commercial product, with a CE mark, called Inductigraft.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
