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Development and validation of a NANOGold immunoassay for the detection of vascular endothelial growth factor (VEGF) in human serum using inductively coupled plasma mass spectrometry.

My publications focus on novel bio-analytical applications of ICP-MS, and in collaboration with AstraZeneca (filippos.michopoulos@astrazeneca.com), continues a research theme that has been established for almost 10 years. This has led to further collaboration between the two institutions developing multi-analyte immunoassay systems. This work was sponsored by AstraZeneca to increase productivity within the DMPK environment and increase collaboration between bioanalysis and biomarker research groups within AstraZeneca. This research was the first attempt to validate this technology for potential use within clinical studies. This work was presented at Winter Plasma Spectrochemistry Conference held in Graz, Austria (Feb 2009).