Output details
5 - Biological Sciences
University of Edinburgh
Article title
A Catalytic Role for Mod5 in the Formation of the Tea1 Cell Polarity Landmark
Type
D - Journal article
Title of journal
Current Biology
Article number
-
Volume number
20
Issue number
19
First page of article
1752
ISSN of journal
0960-9822
Year of publication
2010
Number of additional authors
4
Additional information
This paper describes a combined experimental and modelling analysis of in vivo spatiotemporal dynamics of fission yeast cell-polarity regulatory proteins Tea1 and Mod5. Fission yeast serves as a ‘model’ system for eukaryotic cell polarity, and the results suggest a new paradigm for cytoskeleton-based regulation of cell polarity. To produce this required both experimental and modelling expertise. Sawin provided the experimental genetics, biochemistry and imaging. Goryachev carried out the computational modelling. Both were co-corresponding authors.
Interdisciplinary
Yes
Cross-referral requested
-
Research group
A - Cell and Structural Biology
Citation count
12
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
