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Pseudostatic and Dynamic Nanomechanics of the Tunica Adventitia in Elastic Arteries Using Atomic Force Microscopy

The tunica adventitia, a seldom studied fibrous collagenous structure found on all blood vessels (arteries and veins), is characterised for the first time using advanced atomic force microscopy (AFM) nanoindentation techniques. Here, we determine the mechanical and visco-elastic properties of the tunica adventitia (aorta and pulmonary artery); relate these to the structural components of the tissue; further linking this to their anatomical role with a view for tissue engineering applications. The details of this paper on the nano-mechanics of arterial tunica adventitia were accepted and presented at the national annual SPM conference series run by the Royal Microscopy Society.