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13 - Electrical and Electronic Engineering, Metallurgy and Materials

University of York

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Article title

Measurement of the efficiency of cell membrane electroporation using pulsed ac fields

Type

D - Journal article

DOI

10.1088/0031-9155/53/17/019

Title of journal

Physics in Medicine and Biology

Article number

Volume number

Issue number

First page of article

4747

ISSN of journal

0031-9155

Year of publication

2008

URL

http://iopscience.iop.org/0031-9155/53/17/019/

Number of additional authors

Additional information

This paper advances the manipulation of human cells with electromagnetic fields. In collaboration with University of Leeds, Leeds Teaching Hospitals and Biology at York, and part-funded through the White Rose Health & Innovation Partnership and PhD studentship schemes, AC pulses are shown to be as effective as the traditional DC pulses for electroporating cells, with the added advantage that at kHz frequencies they produce no neuro-muscular stimulation. This work has been the subject to a patent application (GB0918066.2) and industrial collaboration with Magstim Ltd (john.scandone@magstim.com).

Interdisciplinary

Cross-referral requested

Research group

C - Physical Layer

Proposed double-weighted

Double-weighted statement

Reserve for a double-weighted output

Non-English

English abstract