Output details
12 - Aeronautical, Mechanical, Chemical and Manufacturing Engineering
Loughborough University
Article title
A validated model of GAG deposition, cell distribution, and growth of tissue engineered cartilage cultured in a rotating bioreactor
Type
D - Journal article
Title of journal
Biotechnology and Bioengineering
Article number
-
Volume number
105
Issue number
4
First page of article
842
ISSN of journal
0006-3592
Year of publication
2010
URL
-
Number of additional authors
4
Additional information
This theoretical study of engineered tissue growth reported in this paper has been the first publication to successfully model cartilage tissue growth on the basis of a prior knowledge of cell population and extra-cellular matrix production and destruction rates. The work came out of the EPSRC Grand Challenge project “Regenerative Medicine – a New Industry” led by Prof David Williams at Loughborough University and in collaboration with Keele University and Nottingham University (£4,200,000). It feeds into ongoing activity in the manufacture of mechanically stimulated intervertebral disk tissues.
Interdisciplinary
-
Cross-referral requested
-
Research group
None
Proposed double-weighted
No
Double-weighted statement
-
Reserve for a double-weighted output
No
Non-English
No
English abstract
-
