Output details

Flow across microvessel walls through the endothelial surface glycocalyx and the interendothelial cleft

Using a mathematical model for flow through a serial pathway consisting of the endothelial surface glycocalyx and the endothelial intercellular cleft with junction strands and their discontinuous gaps, the three-dimensional flow has been analysed. The present study predicts the hydraulic conductivity close to the experimental measurements for rat mesentery microvessels by Adamson, Curry et al.(University of California). The tools developed have been applied by researchers working in the areas of micro-vascular permeability and cancer therapy.